- EsoCap’s novel targeted delivery platform is designed to increase mucosal contact time and drug deposition in the esophagus
- ESO-101, EsoCap’s lead product candidate, consists of a capsule with a rolled-up, thin mucoadhesive film filled with the anti-inflammatory corticosteroid, mometasone furoate
- Topline results from ACESO study expected in late 2023
EsoCap AG, the Swiss biotech company dedicated to improving the lives of patients with serious diseases of the upper gastrointestinal tract, reports the completion of patient recruitment in the Phase II ACESO trial. The randomized, placebo-controlled, double-blind study is evaluating the efficacy, tolerability and safety of ESO-101 in 43 adult patients with active eosinophilic esophagitis (EoE) in five European countries. Patients have been randomized 2:1 and are being treated for 28 days. EoE is a rare, chronic, local immune-mediated esophageal disease, characterized clinically by symptoms related to esophageal dysfunction including swallowing disorders, food impaction, heartburn and vomiting, and histologically by eosinophil-predominant inflammation.